Malaria morbidity and mortality following introduction of a universal policy of artemisinin-based treatment for malaria in papua, indonesia: A longitudinal surveillance study

E Kenangalem; JR Poespoprodjo; NM Douglas; FH Burdam; K Gdeumana; F Chalfein; Prayoga; F Thio; A Devine; J Marfurt; G Waramori; S Yeung; R Noviyanti; P Penttinen; MJ Bangs; P Sugiarto; JA Simpson; Y Soenarto; NM Anstey; RN Price

Journal article

Malaria morbidity and mortality following introduction of a universal policy of artemisinin-based treatment for malaria in papua, indonesia: A longitudinal surveillance study

E Kenangalem, JR Poespoprodjo, NM Douglas, FH Burdam, K Gdeumana, F Chalfein, undefined Prayoga, F Thio, A Devine, J Marfurt, G Waramori, S Yeung, R Noviyanti, P Penttinen, MJ Bangs, P Sugiarto, JA Simpson, Y Soenarto, NM Anstey, RN Price

Plos Medicine | PUBLIC LIBRARY SCIENCE | Published : 2019

DOI: 10.1371/journal.pmed.1002815

Download PDF

Abstract

Background Malaria control activities can have a disproportionately greater impact on Plasmodium falciparum than on P. vivax in areas where both species are coendemic. We investigated temporal trends in malaria-related morbidity and mortality in Papua, Indonesia, before and after introduction of a universal, artemisinin-based antimalarial treatment strategy for all Plasmodium species. Methods and findings A prospective, district-wide malariometric surveillance system was established in April 2004 to record all cases of malaria at community clinics and the regional hospital and maintained until December 2013. In March 2006, antimalarial treatment policy was changed to artemisinin combination ..

View full abstract

University of Melbourne Researchers

Angela Devine Author

Julie Simpson Author

Related Projects (3)

CENTRE FOR RESEARCH EXCELLENCE IN MALARIA ELIMINATION

The CRE will work to accelerate progress towards malaria elimination in our region, through Surveillance, to develop better ways to monitor ..

Tropical diseases: Translating discoveries into better health

Major progress being made in control of many infectious diseases occurring in tropical areas, including malaria worms and the bacteria that ..

IMPROVING HEALTH OUTCOMES IN THE TROPICAL NORTH: A MULTIDISCIPLINARY COLLABORATION (HOT NORTH)

Improving Health Outcomes in the Tropical North will strengthen partnerships with research institutions in the NT, Qld, WA, NSW, Vic and SA,..

Grants

Awarded by Wellcome Trust

Funding Acknowledgements

The study was funded by the Wellcome Trust (Senior Fellowship in Clinical Science to RNP 200909), the Bill and Melinda Gates Foundation (OPRA, OPP1054404), and the Australian National Health and Medical Research Council (the HOT NORTH initiative #1131932 and Fellowships to JAS #110975 and NMA #1135820; and the Australian Centre of Research Excellence on Malaria Elimination, ACREME #1134989). The Timika Research Facility and Papuan Community Health Foundation is supported by the Australian Department of Foreign Affairs and Trade (DFAT #74431). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.